Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.8
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 180 mg Ferrous Bisglycinate)(Ferrochel™)
36 mg
200%
Top Medical Research Studies
4
We explored how low-level iron supplementation impacts the gut microbiota in individuals with Irritable Bowel Syndrome (IBS) and in healthy donors. To do this, we conducted anaerobic, pH-controlled in vitro batch cultures using fecal samples from both groups, supplemented with various forms of iron, including ferrous sulphate, nanoparticulate iron, and pea ferritin.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Read More
9.5
Celiac disease linked to IBS symptoms
We explored a fascinating case of a 30-year-old patient who was initially diagnosed with irritable bowel syndrome (IBS) due to vague abdominal symptoms. However, this diagnosis was later challenged when he presented with iron deficiency anemia in our clinic.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Read More
Most Useful Reviews
9
No discomfort noted
32 people found this helpful
Excellent iron dosage! I take it with vitamin C. This iron is very gentle; my digestive tract has experienced no discomfort, only darker stools. It’s a great product at a low price with excellent quality, and my bowels function well while taking this supplement.
Read More
9
Anemia improved significantly
6 people found this helpful
I’m really enjoying this product. After taking two tablets daily for four months, my anaemia has nearly disappeared. I will continue taking it to maintain my health during pregnancy and postpartum.
Read More
9
Improved blood results
2 people found this helpful
My endocrinologist recommended this particular brand for my latent iron deficiency anaemia. I’ve noticed improvements in my iron and ferritin levels after a month without any side effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.8
- All Researches
9.5
Celiac disease linked to IBS symptoms
We explored a fascinating case of a 30-year-old patient who was initially diagnosed with irritable bowel syndrome (IBS) due to vague abdominal symptoms. However, this diagnosis was later challenged when he presented with iron deficiency anemia in our clinic.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Read More
4
We explored how low-level iron supplementation impacts the gut microbiota in individuals with Irritable Bowel Syndrome (IBS) and in healthy donors. To do this, we conducted anaerobic, pH-controlled in vitro batch cultures using fecal samples from both groups, supplemented with various forms of iron, including ferrous sulphate, nanoparticulate iron, and pea ferritin.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
No discomfort noted
32 people found this helpful
Excellent iron dosage! I take it with vitamin C. This iron is very gentle; my digestive tract has experienced no discomfort, only darker stools. It’s a great product at a low price with excellent quality, and my bowels function well while taking this supplement.
Read More
9
Anemia improved significantly
6 people found this helpful
I’m really enjoying this product. After taking two tablets daily for four months, my anaemia has nearly disappeared. I will continue taking it to maintain my health during pregnancy and postpartum.
Read More
9
Improved blood results
2 people found this helpful
My endocrinologist recommended this particular brand for my latent iron deficiency anaemia. I’ve noticed improvements in my iron and ferritin levels after a month without any side effects.
Read More
9
Effective stopping
2 people found this helpful
After discovering my restless legs syndrome was due to iron deficiency, I started this supplement and the symptoms stopped. When I miss a dose, it returns, so I know it works.
Read More
0
Ineffective for me
2 people found this helpful
This product doesn't suit me. Despite taking it for severe anaemia, I feel dizzy the next morning and have no bowel movements. Initially, it seemed fine, but my condition worsened after three days.
Read More
Frequently Asked Questions
9
Improved blood results
2 people found this helpful
My endocrinologist recommended this particular brand for my latent iron deficiency anaemia. I’ve noticed improvements in my iron and ferritin levels after a month without any side effects.
7.5
Immediate improvements
1 people found this helpful
After battling dizziness and headaches for years, this supplement improved my condition significantly within a day. However, my bowel movements seem less regular now, so I might try a different brand next time.
0
Not suitable for IBS
This product is okay, but I wouldn't recommend it for anyone with irritable bowel syndrome, as it tends to cause stomach pain.
9
Effective stopping
2 people found this helpful
After discovering my restless legs syndrome was due to iron deficiency, I started this supplement and the symptoms stopped. When I miss a dose, it returns, so I know it works.
9
Anemia improved significantly
6 people found this helpful
I’m really enjoying this product. After taking two tablets daily for four months, my anaemia has nearly disappeared. I will continue taking it to maintain my health during pregnancy and postpartum.
9
No discomfort noted
32 people found this helpful
Excellent iron dosage! I take it with vitamin C. This iron is very gentle; my digestive tract has experienced no discomfort, only darker stools. It’s a great product at a low price with excellent quality, and my bowels function well while taking this supplement.
0
Ineffective for me
2 people found this helpful
This product doesn't suit me. Despite taking it for severe anaemia, I feel dizzy the next morning and have no bowel movements. Initially, it seemed fine, but my condition worsened after three days.
7.5
No issues for child
1 people found this helpful
I’m giving this to my daughter with irritable bowel syndrome, and she has no issues taking it. Her complexion has improved, which is promising.
0
Constipation occurred
It seems this iron supplement is meant to cause less constipation, but I still became constipated. I would like to continue taking it if it doesn't affect my bowel movements negatively.
0
Bowel movement problems
I purchased this for my wife to boost her iron levels, but it seems to be causing some problems with her bowel movements.
References
- Poveda C, Pereira DIA, Lewis M, Walton GE. The Impact of Low-Level Iron Supplements on the Faecal Microbiota of Irritable Bowel Syndrome and Healthy Donors Using In Vitro Batch Cultures. Nutrients. 2020;12. doi:10.3390/nu12123819
- Elmakki EE. Celiac Disease Initially Misdiagnosed as Irritable Bowel Syndrome: Case Report. Cureus. 2012;4:e71. doi:10.7759/cureus.71
